Spectradyne's nCS1 instrument relies on nanofabricated disposable analysis cartridges. These microfluidic devices are based on a unique patented nanoparticle analyzer (NPA) technology that uses resistive pulse sensing. This enables the electrical detection of nanoparticles as they pass one by one through a nanoconstriction. A single nanoparticle increases the electrical resistance of the suspending fluid as it passes through the nanoconstriction, giving rise to a voltage pulse whose size is proportional to the nanoparticle volume and whose duration of the pulse gives the velocity.
Different size cartridges give access to different size ranges of nanoparticles, ranging from 40 nm in diameter up to several micrometers.
Read about our microfluidic technology.
Spectradyne's nCS1 provides accurate, high-resolution particle size and concentration distributions for particles of all material types. The use of resistive pulse sensing for detecting the particle size responds the same way when presented with particles of biological, organic or inorganic origin, giving e.g. the same result for gold NPs, virus and lipids of the same diameter. For more information or to arrange a demonstration of the technology, please contact us.
Spectradyne is a world leader in the microfluidic measurement of nanoparticles.
Nanoparticle analysis using resistive pulse sensing avoids many of the difficulties associated with DLS and optical tracking. Spectradyne is the only company providing microfluidic particle size analysis, now combined with single particle fluorescence.
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