Spectradyne's nCS1 instrument provides a unique platform for the rapid quantitative measurement of nanoparticles in solution. The method used to perform particle size analysis is electrical in nature, so does not rely on an optical index contrast to distinguish particles from their suspending medium. The instrument measures individual nanoparticles and rapidly accumulates statistically-reliable distributions of particle sizes with quantitative concentration information. This unique capability separate the nCS1 from any other instrument on the particle size analysis marketplace.
See an overview of Spectradyne's unique technology, incorporating disposable microfluidic cartridges and yielding quantitative concentrations versus particle diameters over a wide range of sizes.
Read about the specifications for Spectradyne's nCS1TM, showing the range of particle sizes, concentrations and sample properties that you can measure with this unique technology.
Watch a video of the nCS1 in action!
Spectradyne's technology uses highly-engineered microfluidic cartridges for sample particle size analysis. Leveraging advances in semiconductor processing techniques, these cartridges include engineered features that make the Resistive Pulse Sensing technique practical and easy to use at the nanoscale. Some of the benefits our customers appreciate include: 1000-fold smaller sample volume required for analysis (only 3 microliters), no time spent cleaning flow cells between samples, and embedded fluidic features in each cartridge that prevent the clogging behaviors seen in other simplistic implementations of the method. Pre-calibrated at the factory so you don't have to, the microfluidic analysis cartridges are at the heart of Spectradyne's technology.
In the table below we display the different cartridge specifications that are available for particle size analysis. You can also view a cartridge map for cartridge selection.
Read about our microfluidic technology.
Microfluidic cartridges come in different two formats:
We discuss the nCS1 technology and present detailed measurement results.
Software generates histograms of particle diameters, yielding the concentration spectral density (CSD) with units of nanoparticles per unit volume per unit diameter (particles-mL-1-nm-1). This quantitative measure can easily be converted to histograms representing the number of particles in any desired bin width; the CSD is a measurement-independent property of the analyte. Good statistics can be obtained in a few seconds. A more technical description of the measurement platform may be found in J.-L. Fraikin et al., Nature Nanotechnology (2011).
Spectradyne's nCS1 provides accurate, high-resolution particle size analysis and concentration distributions for particles of all material types. The use of resistive pulse sensing for detecting the particle size responds the same way when presented with particles of biological, organic or inorganic origin, giving e.g. the same result for gold NPs, virus and lipids of the same diameter. For more information or to arrange a demonstration of our particle size analysis technology, please contact us.