The Original MRPS Instrument
nCS1™ Particle Analyzer
The instrument that introduced Microfluidic Resistive Pulse Sensing to nanoparticle analysis. The nCS1 delivers accurate size distributions and absolute particle concentration from just 3 µL — for any particle type, regardless of optical properties.
Why the nCS1
The instrument that proved MRPS
Looking for the current-generation model?
The nCS2 is Spectradyne's latest MRPS instrument — featuring an improved cartridge interface and the same proven measurement technology as the nCS1. New customers are directed to the nCS2 for all new installations.
MRPS vs. Light Scattering
Why the nCS1 measured what others couldn't
When DLS and NTA were the only practical options, the nCS1 introduced a fundamentally different approach: Microfluidic Resistive Pulse Sensing measures each particle individually by electrical displacement. No optical scattering bias. No ensemble averaging. Accurate size distributions and absolute particle concentration in samples that confound light-based instruments.
Validated against CryoTEM
MRPS sizing has been independently validated against cryogenic transmission electron microscopy — the accepted gold standard for nanoparticle sizing. Read the application note for head-to-head data.
See detailed comparisons: DLS vs. MRPS NTA vs. MRPS
Applications
Proven across the full range of nanoparticle samples
The nCS1 has been deployed in research and industrial labs worldwide to characterize the biological and synthetic nanoparticles that conventional light-scattering instruments cannot reliably measure.
Ready to see the nCS1 in action?
Submit your own sample for a free measurement run, or schedule a live demo with our applications team.
Current generation
Upgrade to the nCS2
The nCS2 is Spectradyne’s current-generation MRPS instrument, building on the same proven measurement technology as the nCS1 with an improved cartridge interface and updated platform. All new instrument installations ship as nCS2.
