The World Leader in Microfluidic Nanoparticle Analysis
Watch and learn more about the power of our Technology
See how we make every particle count
Spectradyne’s instruments use microfluidic technology combined with nanotechnology to detect and measure every particle in your formulation. We have developed a unique implementation of microfluidic resistive pulse sensing (MRPS), which uses electrical sensing to measure the diameter of each particle as it passes through a nanoconstriction, providing real-time sizing and concentration information.
Applications of our Technology
Quickly and accurately quantify your extracellular vesicles. Enhance the rigor and reproducibility of your science by measuring the absolute concentration and size of your EVs with our instruments. Control for biological variability with accurate measurements at the nano-scale.
Detect formulation instabilities dramatically faster. Turn weeks into minutes by quantifying protein aggregates with our instruments while they are still too small to be detected by conventional optical techniques. Save 1000-fold in time by measuring 10-fold smaller at the nano-scale.
Liposomes & Lipid Nanoparticles
Directly measure the dose of your LNP or liposome formulation for the first time. Eliminate the guesswork of using indirect techniques by directly measuring particle concentration and size with our instruments. Learn how much payload you are really administering in your studies.
Measure the absolute concentration of your virus in minutes. Save time and materials by directly counting virus with our instruments instead of live biological titer. Start dreaming of experiments that depend on real-time tracking of virus concentration.
Gene Therapy and Nanomedicine
Gene therapy vectors and nanomedicines come in many types and sizes, and their accurate quantification is critical at all stages of research and product development. Our instruments quantify all types of nanoparticle-based therapeutics quickly and accurately. Assess concentration, size, purity, and stability using only 3 microliters of your precious sample.
Many modern materials rely on nanoparticle ingredients to perform as intended, including paints, inks, cosmetics, semiconductor polishing slurries, and even foods. Spectradyne’s nCS1 is faster and more quantitative than conventional particle characterization methods, and delivers important new insights into the composition and stability of these ubiquitous materials.
A head-to-head comparison
The chart below shows a direct comparison of measurement of a polydisperse polystyrene nanoparticle sample containing 52nm, 94nm, 122nm, and 150nm particles on our nCS1TM instrument, Optical tracking, and DLS. As you can see, neither Optical Tracking nor DLS can resolve the mixture. Spectradyne’s technology accurately resolves each distribution and gives quantitative concentrations.
“The nCS1 is fast, accurate, and easy to use for routine EV quantification. We looked at other nanoparticle measurement solutions and the nCS1 is the only instrument that could measure the size of every nanoparticle of interest in as little as 3 uL of volume. Moreover, their customer service is superb and have went out of their way to ensure our nCS1 is always functioning well.”
Joseph Sedlak, Co-Founder at Mercy BioAnalytics
“The nCS1 can quantitate phage particles in minutes using only a few microliters of the sample, significantly reducing time and money spent on biological methods.”
Angela Soriaga, Ph.D., Senior Scientist, Armata Pharmaceuticals Inc
“The nCS1 works very well in optimizing time of virus harvest by monitoring virus titers in minutes during propagation. It is also a great tool to check purity of viral preps prior to downstream applications such as gene therapy.”
Farhad Imani, Ph.D., President, ViraSource Labs
“The nCS1 is fast, accurate, and easy to use for routine particle quantification.”
Hok Hei Tam, Flagship Labs 62 Inc
“The nCS1 has rapidly become an indispensable tool for accurately quantifying EVs in my lab.”